Spirometrically controlled quantitative CT for detection of pulmonary function in silica-exposed workers.
- Author:
Ping HAN
1
;
Fan ZHANG
;
Fang LIU
;
Gansheng FENG
;
Heshui SHI
;
Jinlong ZHENG
;
Yonghua LIU
;
Youlin LI
Author Information
- Publication Type:Journal Article
- MeSH: Humans; Occupational Exposure; Respiratory Function Tests; Sensitivity and Specificity; Silicon Dioxide; adverse effects; Spirometry; Tomography, X-Ray Computed; methods; Vital Capacity
- From: Chinese Journal of Industrial Hygiene and Occupational Diseases 2002;20(2):106-109
- CountryChina
- Language:Chinese
-
Abstract:
OBJECTIVETo evaluate the diagnostic value of spirometrically controlled quantitative CT in silica-exposed workers.
METHODSWhole lung spiral scans at 50% vital capacity (VC) and image with high resolution CT(HRCT) at 10% VC and 90% VC level and 5 cm above/below carina were performed in 62 silica-exposed workers and 54 healthy adults. Automatic evaluation software, Pulmo, was used to evaluate the quantitative parameters and compared with clinical pulmonary function tests.
RESULTS9 workers with emphysema were detected by CT scans from 62 silica-exposed workers. The quantitative parameters of 10% VC and 90% VC were significantly different between the silica-exposed workers and the controls (P < 0.05). With the increasing of length of exposure to silica dust, the difference showed a ladder-like rising.
CONCLUSIONSpirometrically controlled quantitative CT is a sensitive, accurate and objective method. It is superior to conventional CT and pulmonary function tests for the early detection in silica-exposed workers, espicially for detecting early stage of small airway disease.
