Relationship between blood NO and PaO2 or PaCO2 levels of patients with acute carbon monoxide poisoning.
- Author:
Aijun QU
1
;
Tiejun WU
;
Hui TIAN
;
Zhijun LIU
;
Suocheng TIAN
Author Information
- Publication Type:Journal Article
- MeSH: Acute Disease; Carbon Dioxide; blood; Carbon Monoxide Poisoning; blood; Humans; Nitric Oxide; blood; Oxygen; blood
- From: Chinese Journal of Industrial Hygiene and Occupational Diseases 2002;20(4):304-305
- CountryChina
- Language:Chinese
-
Abstract:
OBJECTIVETo investigate the relationship between blood nitrogen monoxide(NO) and PaO2 or PaCO2 levels in patients with severe and moderate acute carbon monoxide poisoning.
METHODThe blood levels of NO in patients with severe and moderate acute carbon monoxide poisoning was assayed with nitrate reductase method, and its correlation with the blood levels of PaO2 and PaCO2 was analyzed.
RESULTSThe blood level of NO in patients with severe and moderate acute carbon monoxide poisoning were (36.6 +/- 9.9) and (35.7 +/- 10.7) mumol/L respectively, significantly lower than that of control group[(64.9 +/- 14.3) mumol/L, P < 0.01], but there was no significant difference between moderate and severe patients(P > 0.05). The analysis of linear correlation showed that there was significant positive correlation between NO and PaO2 but not PaCO2.
CONCLUSIONAnoxia of patients with acute carbon monoxide poisoning may be an important cause to reduce NO level in blood. This study provides the basis for low NO concentration inhalation in treatments of acute carbon monoxide poisoning.
