The investigation on the changes of haematological parameters in the occupationally lead exposed workers.
- Author:
Shanzhuo PENG
1
;
Chunsheng ZHANG
;
Chaohe WANG
;
Mingzhi WEI
;
Jie ZHANG
;
Zhuoli XI
;
Xiaoxia YANG
Author Information
- Publication Type:Journal Article
- MeSH: Anemia; chemically induced; Erythrocytes; drug effects; Female; Hematocrit; Hemoglobins; analysis; Humans; Lead; blood; toxicity; Male; Occupational Exposure; adverse effects
- From: Chinese Journal of Industrial Hygiene and Occupational Diseases 2002;20(5):334-335
- CountryChina
- Language:Chinese
-
Abstract:
OBJECTIVETo estimate the level of blood lead and some haematological parameters in the workers occupationally exposed to lead so as to know the effect of lead exposure on hematopoietic system in exposed workers.
METHODSThe graphite furnace atomic absorption spectrocopy was used to determine blood lead (BPb). The haematological parameters were determined by Sysmex KX-21 automated haematology analyzer.
RESULTSHemoglobin (Hb) in the lead-absorption group[male: (129.3 +/- 12.3) g/L, female: (112.2 +/- 9.4) g/L], and hematocrit (HCT) in the lead-absorption group[male: (0.338 +/- 0.030) L/L, female: (0.302 +/- 0.028) L/L] were significantly lower than those in normal people group and lead-exposed group (P < 0.05, P < 0.01). The relationships between BPb and Hb, HCT were weakly negative correlation. Red cell distribution width (RDW) in the lead-absorption group(male: 16.68% +/- 0.80%, female: 16.98% +/- 0.98%) were significantly higher than those in normal people group and lead exposed group, and RDW in lead exposed group (male: 14.77% +/- 0.83%, female: 14.92% +/- 1.13%) were higher than that in normal people group. BPb was weakly positively correlated with RDW.
CONCLUSIONHb, HCT and RDW were three indices which may reflect the occurrences and degrees of anaemia in lead exposed workers.
