Pulmonary Hypertension in End-Stage Renal Disease Patients with Maintenance Hemodialysis.
- Author:
Chang Su CHUNG
1
;
Young Ki LEE
;
Jong Soo CHOI
;
Seung Min LEE
;
Young Rim SONG
;
Soo Jin KIM
;
Tae Jin PARK
;
Jieun OH
;
Jang Won SEO
;
Jong Woo YOON
;
Ja Ryong KOO
;
Hyung Jik KIM
;
Jung Woo NOH
;
Seonghoon CHOI
Author Information
1. Department of Internal Medicine, Kidney Research Institute, College of Medicine, Hallym University, Seoul, Korea. km2071@unitel.co.kr
- Publication Type:Original Article
- Keywords:
Hypertension;
Pulmonary;
Hemodialysis;
Arteriovenous fistula
- MeSH:
Arteriovenous Fistula;
Dialysis;
Echocardiography, Doppler;
Humans;
Hypertension;
Hypertension, Pulmonary;
Kidney Failure, Chronic;
Prevalence;
Pulmonary Artery;
Renal Dialysis;
Risk Factors
- From:Korean Journal of Nephrology
2011;30(1):48-52
- CountryRepublic of Korea
- Language:Korean
-
Abstract:
PURPOSE: Pulmonary hypertension can occur from diverse etiologies. It was reported that pulmonary hypertension also complicated dialysis patents, but the exact mechanisms were not determined. The aim of this study was to evaluate the prevalence and risk factors of pulmonary hypertension in maintenance hemodialysis patients. In addition, we studied the relationship between pulmonary hypertension and arteriovenous access. METHODS: Fifty-nine chronic hemodialysis patients underwent clinical evaluation. Pulmonary artery pressure (PAP) was estimated by Doppler echocardiography. Pulmonary hypertension was defined as PAP > or =35 mmHg. RESULTS: Mean PAP value of subjects was 39.3+/-13.2 mmHg. Pulmonary hypertension was found in 31 (53%) of patients receiving hemodialysis (49.0+/-10.6 mmHg; range 37 to 84 mmHg). Clinical and biochemical parameters did not differ significantly between patients with pulmonary hypertension and without pulmonary hypertension. In 19 patients, PAP was elevated from 27.8+/-10.2 mmHg to 41.8+/-11.9 mmHg (p<0.001) after onset of hemodialysis via arteriovenous fistula. And pulmonary hypertension developed in 12 of 15 patients with normal PAP after onset of hemodialysis treatment. CONCLUSION: The prevalence of pulmonary hypertension was high, and hemodialysis via arteriovenous access may be involved in the development of pulmonary hypertension.
