A Case of Adult Minimal Change Nephrotic Syndrome Associated with Thin Basement Membrane Nephropathy.
- Author:
Ji Eun SONG
1
;
Ki Hoi KIM
;
Jeong Gwan KIM
;
Wang Guk OH
;
Sung Hyun PARK
;
Kyung Chul MOON
;
Jung Hwa KIM
;
Kwang Young LEE
Author Information
1. Department of Internal Medicine, Presbyterian Medical Center, Jeonju, Korea. josephep@paran.com
- Publication Type:Case Report
- Keywords:
Minimal change nephrotic syndrome;
Glomerular basement membrane;
Hematuria
- MeSH:
Adult;
Basement Membrane;
Biopsy;
Edema;
Electrons;
Female;
Foot;
Glomerular Basement Membrane;
Glomerulonephritis, IGA;
Glomerulonephritis, Membranous;
Glomerulosclerosis, Focal Segmental;
Hematuria;
Humans;
Nephrosis, Lipoid;
Proteinuria
- From:Korean Journal of Nephrology
2011;30(1):94-97
- CountryRepublic of Korea
- Language:Korean
-
Abstract:
Thin basement membrane nephropathy (TBMN) is characterized by persistent hematuria, mild proteinuria, normal renal function and family history of hematuria. Many studies report that TBMN commonly occurs together with other glomerular diseases such as minimal change nephrotic syndrome, membranous nephropathy, IgA nephropathy and focal segmental glomerulosclerosis. Especially, the case of TBMN with minimal change nephrotic syndrome has been rare. We report a case of adult minimal change nephrotic syndrome with TBMN in a 44-year-old female with general edema and microscopic hematuria. On renal biopsy, electron microscopic examination demonstrated diffuse thinning of glomerular basement membrane with the thickness less than 250nm and diffuse foot process effacement. Treatment with corticosteroid resulted in complete remission of proteinuria.
