Effect of anxiety and depression on the recurrence of persistent atrial fibrillation after circumferential pulmonary vein ablation.
- Author:
Sheng-bo YU
1
;
Wei HU
;
Qing-yan ZHAO
;
Mu QIN
;
He HUANG
;
Hong-ying CUI
;
Cong-xin HUANG
Author Information
- Publication Type:Journal Article
- MeSH: Aged; Anti-Asthmatic Agents; therapeutic use; Anxiety; complications; Atrial Fibrillation; drug therapy; pathology; psychology; surgery; Catheter Ablation; Depression; complications; Female; Humans; Male; Middle Aged; Pulmonary Veins; surgery; Treatment Outcome
- From: Chinese Medical Journal 2012;125(24):4368-4372
- CountryChina
- Language:English
-
Abstract:
BACKGROUNDThe effects of anxiety and depression on the recurrence of persistent atrial fibrillation (AF) after circumferential pulmonary vein ablation (CPVA) are not clear. Whether CPVA can alleviate the anxiety and depression symptoms of persistent AF patients is unknown.
METHODSOne hundred and sixty-four patients with persistent AF, of which 43 treated with CPVA (CPVA group) and 103 treated with anti-arrhythmics drugs (medicine group), were enrolled. The Zung Self-Rating Anxiety Scale (SAS), and Zung Self-Rating Depression Scale (SDS) were assessed before and 12 months after treatment in all patients.
RESULTSThe scores of SAS (40.33 ± 7.90 vs. 49.76 ± 9.52, P < 0.01) and SDS (42.33 ± 8.73 vs. 48.17 ± 8.77, P < 0.01) decreased 12 months after CPVA. Over 12 months follow-up, AF relapsed in 17 patients in CPVA group. Compared with the data in the recurrent group (17 patients), the scores of SAS and SDS were significantly lower in the non-recurrent group (26 patients) at baseline. The results of multivariate Logistic regression analysis showed normal scores of SAS and SDS were the independent risk factors of AF recurrence after CPVA.
CONCLUSIONSAnxiety and depression increase the recurrence risk of persistent AF after CPVA. CPVA can ameliorate the anxiety and depression symptoms in patients with persistent AF.
