Preliminary studying the hypoglycemic effect of smilax glabra in mice
- Author:
Xuan Ngoc Nguyen
- Publication Type:Journal Article
- Keywords:
Traditional medicine
- MeSH:
Hypoglycemic Agents;
Mice
- From:Journal of Medical Research
2001;15(2):3-6
- CountryViet Nam
- Language:Vietnamese
-
Abstract:
The methanol extract from rhizomes of Smilax glabra Roxb - Smilacaceae reduced the blood glucose of normal mice. The maximal hypoglycemic effect was about 36% with the dose of 100mg/kg-body weight per intraperitoneal route, and about 56% with 200 mg/kg/ip. The oral administration of 200 mg/kg body weight doesn't decrease yet the blood glucose. The LD50 per oral route in mice is 2500 mg/kg body weight
