Study of correlation factors with left ventricular hypertrophy during cardiac hypertrophy induced hypertension and regression in rats.
- Author:
Hai-ying LI
1
;
Zi-quan LIU
;
Chang-qing TONG
;
Li QI
Author Information
- Publication Type:Journal Article
- MeSH: Animals; Blood Pressure; Heart Rate; Hypertension; metabolism; physiopathology; Hypertrophy, Left Ventricular; metabolism; physiopathology; Male; Neuropeptide Y; metabolism; Rats; Rats, Wistar
- From: Chinese Journal of Applied Physiology 2003;19(2):127-130
- CountryChina
- Language:Chinese
-
Abstract:
AIMTo investigate the relations between left ventricular hypertrophy and systolic blood pressure (SBP), diastolic blood pressure (DBP), mean arterial pressure (MAP), neuropeptide Y (NPY) during cardiac hypertrophy and regression.
METHODSBlood pressure and heart rate were recorded with polygraph channel biologic message system. NPY in plasma and myocardium were measured with Radioimmunoassay. Correlation coefficient were calculated with SPSS software.
RESULTSThere were positive correlations between SBP, DBP, MAP, NPY in the cardiac tissue and cardiac coefficient (LVW/BW). There was no correlations between cardiac coefficient and heart rate (HR), NPY in plasma.
CONCLUSIONHypertension is one of cardiac hypertrophy factors, SBP correlate better with LVW/ BW than DBP. SBP, DBP, MAP, NPY in cardiac tissue has correlative tendency with LVW/BW.
