Risk factors for capillary leak syndrome in neonates.

Author: Yu-Mei LI ¹ ; Jie RAN ; Heng LI ; Chao-Ying YAN
Author Information

1. Department of Neonatology, First Hospital of Jilin University, Changchun, China.
Publication Type:Journal Article
MeSH: Capillary Leak Syndrome; etiology; Female; Humans; Infant, Newborn; Male; Retrospective Studies; Risk Factors
From: Chinese Journal of Contemporary Pediatrics 2011;13(9):708-710
CountryChina
Language:Chinese
Abstract:
OBJECTIVETo study the risk factors for capillary leak syndrome (CLS) in neonates.
METHODSThe clinical data of 52 neonates with CLS (case group) were retrospectively reviewed. Fifty hospitalized neonates without CLS were used as the control group. The possible factors for the development of CLS were identified by univariate analysis. The independent risk factors for CLS were determined by multivariate logistic regression analysis.
RESULTSThe univariate analysis showed that the incidences of hyperglycemia, respiratory distress syndrome (RDS), sepsis and cold injury syndrome in the case group were significantly higher than those in the control group (P<0.05). The logistic regression analysis showed that sepsis (OR=5.004, P=0.001), RDS (OR=3.880, P=0.013) and cold injury syndrome (OR=3.207, P=0.023) were the independent risk factors for the development of CLS.
CONCLUSIONSRDS, sepsis and cold injury syndrome are independent risk factors for CLS in neonates. Hyperglycemia may be associated with the development of CLS.