Relationship between serum ferritin levels and susceptibility to attention deficit hyperactivity disorder in children: a Meta analysis.
- Author:
Li-Na TAN
1
;
Hai-Yan WEI
;
Yao-Dong ZHANG
;
Ai-Lian LU
;
Ying LI
Author Information
- Publication Type:Journal Article
- MeSH: Attention Deficit Disorder with Hyperactivity; blood; etiology; Child; Ferritins; blood; Humans
- From: Chinese Journal of Contemporary Pediatrics 2011;13(9):722-724
- CountryChina
- Language:Chinese
-
Abstract:
OBJECTIVETo study the possible relationship between serum ferritin levels and susceptibility to attention deficit hyperactivity disorder (ADHD) in children.
METHODSThe papers relating to the relationship between serum ferritin levels and susceptibility to childhood ADHD were searched in the Database CBM, CNKI, VIP and PubMed. The Meta-analysis software RevMan 5.0 was used for the heterogeneity test and for the pooled OR calculation. Sensitivity and publication bias analysis were performed.
RESULTSFive control studies were included for the Meta analysis, including 258 cases of ADHD and 138 control cases. There was heterogeneity in the studies on the relationship between serum ferritin levels and susceptibility to childhood ADHD (P=0.003). So the studies were analyzed using the random-effect model. The pooled OR of serum ferritin levels and susceptibility to childhood ADHD was -23.09 (95%CI:-33.06-13.13; P<0.00001). The funnel plots did not indicate the existence of publication bias.
CONCLUSIONSThe results from present Meta analysis can prove that serum ferritin levels are associated with susceptibility to childhood ADHD.
