Experiment on the sexual virility of immature mice immunized with LHRH fusion protein vaccine.
- Author:
Qin-Qin PAN
1
;
Yu-Gui CUI
;
Guang-Ming GONG
;
Chuan-Yi JI
;
Yong PAN
;
Xing-Hai WANG
Author Information
- Publication Type:Journal Article
- MeSH: Animals; Antibodies; metabolism; Female; Gonadotropin-Releasing Hormone; immunology; Male; Mice; Mice, Inbred ICR; Pregnancy; Recombinant Fusion Proteins; immunology; Sexual Development; immunology; Sexual Maturation; immunology; Sperm Motility; Testosterone; analysis; Vaccines, Synthetic; immunology
- From: National Journal of Andrology 2005;11(8):566-573
- CountryChina
- Language:Chinese
-
Abstract:
OBJECTIVETo observe the sexual virility of immature immature male mice were divided into a pre-ablactation group (n 10). The first two groups were immunized with the LHRH fusion proportion of pregnant female mice, the morphological and histological examined to conform the emasculating effect of the vaccine. When ted with testosterone (1.0 ml each) , the post-ablactation ones were rameters.
RESULTSThe sexual virility of the immature mice immunized in 3 -4 months.
CONCLUSIONThe LHRH fusion protein vaccine mice after ablactation, and the sexual virility can recover in the pre-ablactation decrease.