Effect of compound nonoxinol on the inhibition of bacteria in vitro.
- Author:
Jie CAO
1
;
Wei-dong LI
Author Information
- Publication Type:Journal Article
- MeSH: Anti-Infective Agents, Local; pharmacology; Candida albicans; drug effects; Dose-Response Relationship, Drug; Drug Combinations; Neisseria gonorrhoeae; drug effects; Nonoxynol; pharmacology; Povidone-Iodine; pharmacology
- From: National Journal of Andrology 2005;11(9):661-663
- CountryChina
- Language:Chinese
-
Abstract:
OBJECTIVETo study the effect of compound nonoxinol on the inhibition of bacteria in vitro.
METHODSThe minimal bactericidal concentration (MBC) and minimal bactericidal time (MBT) of nonoxinol providine iodine and compound nonoxinol, composed of nonoxinol and providine iodine were determined by inhibiting C. albicans and N. gonorrhoeae.
RESULTSNonoxinol alone showed no inhibiting effects on bacteria. The MBT was 2 minutes for both compound nonoxinol and providine iodine, but the MBC of providine iodine was higher than that of compound nonoxinol.
CONCLUSIONCompound nonoxinol works better in inhibiting bacteria than either nonoxinoother or providine iodine used alone.
