Cryosurgical ablation for 23 cases of prostate cancer guided by rectal ultrasound.
- Author:
Qing WU
1
;
Xue-song WANG
;
Jian-xin QIAN
;
Jia-xing ZHANG
;
Qing XU
;
Chuan-wu CAO
;
Xiao-qiang GU
;
Yi-zhou LUO
;
Jie-jun WANG
Author Information
- Publication Type:Journal Article
- MeSH: Adult; Aged; Aged, 80 and over; Cryosurgery; methods; Follow-Up Studies; Humans; Male; Middle Aged; Prostate-Specific Antigen; blood; Prostatic Neoplasms; pathology; surgery; Rectum; diagnostic imaging; Ultrasonography
- From: National Journal of Andrology 2005;11(9):670-673
- CountryChina
- Language:Chinese
-
Abstract:
OBJECTIVETo detect the short-term clinical and side effects of cryosurgical ablation for prostate cancer.
METHODSThe ENDOCAm cryosurgical system with 2 mm Cryo-probes was used to treat the prostate cancer guided by rectal ultrasonic. 1. Completeness of freeze; 2. Complications; 3. The changes of PSA and PSMA before and after operation were observed respectively.
RESULTS1. The completeness of freeze rate and non-completeness of freeze rate were 34.8% (8/23) and 65.2% (15/23) showed by MRI 3 weeks later after operation; the biopsy results showed that tumor positive rates in completeness of freeze group and non-completeness of freeze group were 0 and 20% (3/15) respectively after 6 months. 2. The incontinence rate was 13%, and all recovered during 1 month; and the erectile dysfunction rate post-operation was 56.2% (9/16). 3. The levels of PSA before and after cryosurgical ablation were (32.98 +/- 35. 50) microg/L, (11.65 +/- 26. 51) microg/L respectively (P < 0.05). PSMA increased significantly after the cryosurgical ablation.
CONCLUSIONThe short-term curative effects of cryosurgical ablation, which guided by rectal ultrasound for prostate cancer is satisfied with low complication rate and minor vulnus.
