Intracytoplasmic sperm injection can improve the fertilization limitation following in vitro fertilization during previous cycles.
- Author:
Ling-bo CAI
1
;
Ting FENG
;
Juan CHEN
;
Yun QIAN
;
Jia-yin LIU
;
Yan ZHANG
Author Information
- Publication Type:Journal Article
- MeSH: Female; Fertilization; Fertilization in Vitro; Humans; Male; Oocytes; Pregnancy; Pregnancy Rate; Sperm Injections, Intracytoplasmic
- From: National Journal of Andrology 2005;11(12):895-899
- CountryChina
- Language:Chinese
-
Abstract:
OBJECTIVETo evaluate whether or not intracytoplasmic sperm injection (ICSI) can improve previous fertilization limitation on conventional in vitro fertilization (IVF).
METHODSOne hundred and thirty-six completed cycles in 113 patients with ICSI treatment were grouped. Group 1 was 106 cycles perform ICSI because of male factor, and group 2 was other 30 cycles with the history of fertilization failure and fertilization rate < 20% on conventional IVF, also assembling the cycles in group 2 according to the fertilization rate.
RESULTSThere was no significant difference between two groups in the rates of normal fertilization(70.49% vs 72.02%), good quality embryos (38.28% vs 38.81%), and clinical pregnancy (40.57% vs 40.00%) (P > 0.05). The fertilization rate of a majority of cycles (70.00%, 21/30) in group 2 was higher than 50%, and the mean of fertilization rates was 79.79%.
CONCLUSIONICSI can improve the fertilization limitation following IVF during previous cycles, and the fertilization rates was similar to those treated ICSI because of male factor.
