Preliminary study on hypoglycemic effect of Smilax glabra Roxb. on mice
- Author:
Xuan Ngoc Nguyen
- Publication Type:Journal Article
- Keywords:
Traditional medicine
- MeSH:
Hypoglycemic Agents;
Mice
- From:Pharmaceutical Journal
1998;272(12):12-13
- CountryViet Nam
- Language:Vietnamese
-
Abstract:
The methanol extract of rhizomes of smilax glabra Roxb. Smilacaceae reduced the blood glucose of normal mice. The maximal hypoglycemic effect was about 38% at the dose of 100mg/kg body weight per intraperitoneal route, and about 56% with 200 mg/kg/ip. The oral administration of 200 mg/kg body weight did not decrease yet the blood glucose. The LD50 per intraperitoneal route in mice was 2500 mg/kg body weight