Measurement of exhaled nitric oxide in healthy Chinese
10.3760/cma.j.issn.1673-0860.2009.04.009
- VernacularTitle:健康成人口鼻呼出气一氧化氮含量测定及其影响因素分析
- Author:
Luo ZHANG
1
;
Xue-Rui LUO
;
Cheng-Yao LIU
;
Yan ZHAO
;
De-Min HAN
Author Information
1. 首都医科大学附属北京同仁医院
- Keywords:
Nitric oxide;
Mouth breathing;
Nose;
Exhalation
- From:
Chinese Journal of Otorhinolaryngology Head and Neck Surgery
2009;44(4):302-306
- CountryChina
- Language:Chinese
-
Abstract:
Objective To obtain the normal values of nitric oxide (NO) exhaled throuth nose and mouth in healthy Chinese adults by measuring exhaled NO and analyzing the influencing factors. Methods Eighty healthy Chinese adults were recruited, including 20 males and 60 females. The age ranged from 18 to 44 years old. Chemiluminescence analyzer (NIOX) was used to obtain the values of exhaled NO throuth nose and mouth. The relativity between NO and gender, age, height, body mass index, time, ambient NO were analyzed with Multiple linear regression and correlation. Results Exhaled NO values were (17±8)×10-9 and correlated significantly with height. Regression equation: Y(exhaled nitric oxide) = -58. 524 +0.457X(height, cm),t = -2.985,P <0.01. Transnasal NO values were (819±211) ×10-9 and correlated significantly with age and gender. Regression equation: Y(nasal nitric oxide) = 760. 245 +9.417X1(age) -111. 222X2(gender),t=5. 188,P<0.01. Conclusions Exhaled NO normal values were 17×10-9 and Transnasal NO normal values were 819 × 10-9. Exhaled NO correlated positively with height. Transnasal NO correlated positively with age and negatively with gender.
