Analysis of clinical characters of chronic rhinosinusitis in patients with postirradiated nasopharyngeal carcinoma
10.3760/cma.j.issn.1673-0860.2009.04.011
- VernacularTitle:鼻咽癌放射治疗后继发慢性鼻-鼻窦炎的临床特征分析
- Author:
Huai-Hong CHEN
1
;
De-Hua WU
;
Yong LIANG
;
Xiang-Ping LI
;
Qi LI
;
Wen-Dong TIAN
;
Xiong LIU
Author Information
1. 南方医科大学南方医院
- Keywords:
Nasopharyngeal neoplasms;
Radiotherapy;
Sinusitis
- From:
Chinese Journal of Otorhinolaryngology Head and Neck Surgery
2009;44(4):307-310
- CountryChina
- Language:Chinese
-
Abstract:
Objective To study the characters of chronic rhinosinusitis in patients with irradiated nasopharyngeal carcinoma. Methods There were 65 cases of chronic rhinasinusitis after irradiated nasopharyngeal carcinoma (NPC, experimental group) and 65 cases of common chronic rhinosinusitis (CRS, control group) in the study. The visual analogue scale (VAS) was used to evaluate the intensity of subjective symptoms. Endoscopic finding was recorded and CT results were evaluated by Lund-Mackay scoring system. Results As to the VAS, nasal secretion was significantly more severe in experimental group (7.86±1.62), compared with control group(5.12±1.32, t = 10.541, P <0.01). As to endoscopic finding, middle nasal meatus were clean in 35 (53.8%) cases in experimental group, and 23 cases (35.4%) in control group(χ2=4. 483, P<0. 05). CT score was(7.03±4. 63)in experiment group, and (11.42±3.32) in control group (t=-6.207,P<0.05). The main reason lays in lower CT score and lower involved rate of ostiomeatal complex ,frontal sinus, maxillary sinus, anterior ethmoid sinus. Conclusions The characters of chronic rhinosinasitis in patients with irradiated nasopharyngeal carcinoma is quite different from the common CRS and different therapeutic measures should be taken.
