Preliminary investigation on mechanism of hypoglycemic effect of Smilax glabra Smilacaceae
- Author:
Xuan Ngoc Nguyen
- Publication Type:Journal Article
- Keywords:
Traditional medicine
- MeSH:
Plants, Medicinal;
Hypoglycemic Agents
- From:Pharmaceutical Journal
2001;305(9):18-21
- CountryViet Nam
- Language:Vietnamese
-
Abstract:
The streptozotocin - induced diabetic mice (STZ 300mg/kg/ip), either the methanol extract of rhizomes of Smilax glabra Roxb. - Smilacaceae (SG) or the tolbutamid did not effect the blood sugar, one of the model of insulin - dependent diabetes mellitus (IDDM) with hypoinsulinemia. However, while tolbutamid coundn't decrease epinephrine - induced hyperglycemia in mice. SG suppressed partially this one. The result, suggested that SG reduced the blood sugar by an extra - pancreas mechanism
