Advance of studies on bioactivity of flavonoid-metal complexes.
- Author:
Yanji LIU
1
;
Xiaoyan HE
;
Hua ZUO
;
Qixiong ZHANG
;
Zhubo LI
;
Lunyong SHI
Author Information
1. College of Pharmaceutical Sciences, Southwest University, Chongqing 400715, China. liuyanji111@163.com
- Publication Type:Journal Article
- MeSH:
Animals;
Coordination Complexes;
pharmacology;
Drugs, Chinese Herbal;
pharmacology;
Flavonoids;
pharmacology;
Humans;
Medicine, Chinese Traditional
- From:
China Journal of Chinese Materia Medica
2012;37(13):1901-1904
- CountryChina
- Language:Chinese
-
Abstract:
The flavonoid-metal complexes showed obviously stronger bioactivities such as antibiosis, antivirus, anti-inflammatory, anti-tumor and anti-free-radical, possibly because of the stronger binding force caused by the change in complex structure and accessibility to target spots, or the synergy effect between flavonoids and metallic ions. This essay summarizes studies on bioactivity and mechanism of flavonoid-metal complexes, in order to provide reference for in-depth study and development on effective constituents contained in flavonoid traditional Chinese medicines.
