Chemical constituents contained in Aeschynanthus moningeriae.
- Author:
Huixin LIU
1
;
Haibing LIAO
;
Ke YUAN
Author Information
- Publication Type:Journal Article
- MeSH: Chromatography; methods; Drugs, Chinese Herbal; chemistry; isolation & purification; Magnoliopsida; chemistry; Medicine, Chinese Traditional
- From: China Journal of Chinese Materia Medica 2012;37(13):1963-1967
- CountryChina
- Language:Chinese
-
Abstract:
OBJECTIVETo study chemical constituents contained in Aeschynanthus moningeriae.
METHODThe chemical constituents were separated and purified by column chromatographic methods such as Diaion HP-20, Toyopearl HW-40, Sephadex LH-20, MCI-Gel CHP-20, RP18 and normal phase silica gel. Their structures were identified on the basis of physiochemical property and spectral techniques (1H, 13C-NMR, DEPT, 1H-1H COSY, HSQC, HMBC, HR-MS).
RESULTTwelve compounds were separated and identified as 5,7-dihydroxy-8-C-beta-D-glucosyl-chromone (1), 5-hydroxyl-7,4'-dimethoxyl-flavone (2), 2,3,19, 24-tetrahydroxy-urs12-en-28-oic acid (3), 2,3,19, 24-tetrahydroxy-urs-12-en-28-oic acid ester-28-O-beta-D-gucoside (4), 5-hydroxyl-6,4'-dimethoxyl-7-O-[alpha-L-rhamnosyl-(1-->6)]-beta-D-glucopyranosyl-flavone (5), 5,7,3',4'-tetrahydroxy-6-C-beta-D-glucosyl-flavonol (6), 5,7-dihydroxy-6-C-beta-D-glucosyl-flavonones (7), 5,7, 3',4'-tetrahydroxy-6-C-beta-D-glucosyl-dihydroflavonol (8), daucosterol (9), stigmasterol (10), beta-sitosterol (11), and 3-O-beta-D-glucosyl-stigmasterol (12).
CONCLUSIONCompound 1 is a new compound, while other compounds were separated from this plant for the first time.
