Chemical constituents contained in Macropanax rosthornii.
- Author:
Yongming LUO
1
;
Hua LIU
;
Xiaoying YIN
;
Xide YE
;
Lijie KANG
Author Information
- Publication Type:Journal Article
- MeSH: Araliaceae; chemistry; Chromatography; methods; Drugs, Chinese Herbal; chemistry; Medicine, Chinese Traditional
- From: China Journal of Chinese Materia Medica 2012;37(13):1977-1980
- CountryChina
- Language:Chinese
-
Abstract:
OBJECTIVETo study active constituents of Macropanax rosthornii in treating rheumatoid arthritis.
METHODSilica gel column chromatography, preparative HPLC and modern spectrum techniques were applied for a systematic study on chemical constituents contained in M. rosthornii.
RESULTTwelve compounds were separated from M. rosthornii and identified as serratagenic acid (1), serjanic acid (2), betulinic acid (3), 6beta-hydroxy-3-oxo-olean-12-en-28-oic acid (4), 3-O-alpha-L-arabinopyranosyl serratagenic acid (5), 3-O-alpha-L-arabinopyranosyl serratagenic acid-29-methyl ester (6) , 3-O-alpha-L-arabinopyranosyl serratagenic acid-28-O-beta-D-glucopyranosyl ester (7), scopoletin (8), beta-sitosterol (9), daucosterol (10), 3,4-dihydroxybenzoic acid (11), and stearic acid (12).
CONCLUSIONAbove compounds are separated from M. rosthornii for the first time.
