Chemical constituents and antibacterial activity contained in Caesalpinia millettii.
- Author:
Ping CHEN
1
;
Jun LEI
;
Xudong XU
;
Junshan YANG
Author Information
1. College of Life Science, Jilin Agricultural University, Changchun 130118, China. chenping2009@yahoo.com.cn
- Publication Type:Journal Article
- MeSH:
Anti-Bacterial Agents;
analysis;
Caesalpinia;
chemistry;
Chromatography, High Pressure Liquid;
Isoflavones;
analysis;
pharmacology;
Microbial Sensitivity Tests;
Plant Roots;
chemistry
- From:
China Journal of Chinese Materia Medica
2012;37(14):2105-2107
- CountryChina
- Language:Chinese
-
Abstract:
To study chemical constituents contained in roots of Caesalpinia millettii by HPLC. Six homoisoflavonoids were identified by spectroscopic data and physicochemical property as eucomin (1), intricatinol (2), 8-methoxybonducellin (3), bonducellin (4), 8-methoxyisobonducellin (5) and 3-(4-methoxybenzyl) -5, 7-dimethoxychroman-4-one (6). All compounds were separated from the root of this genus for the first time. An antibacterial screening was made on eight monomeric compounds. Among them, 8-methoxyisobonducellin, intricatinol, bergenin, hyperoside and 11-O-galloylbergenin showed a inhibitory effect on Staphylococcus aureus, Klebsiella Peneumoniae, Beta streptococcus and Aeruginosus bacillus.
