Study on toxicity of uniform design-based compatible use of Veratrum nigrum and asarum.
- Author:
Yanli WANG
1
;
Yuguang WANG
;
Qiande LIANG
;
Zengchun MA
;
Chengrong XIAO
;
Hongling TAN
;
Yue GAO
Author Information
1. PLA General Hospital, Beifing 100853, China. wylhope365@163.com
- Publication Type:Journal Article
- MeSH:
Animals;
Asarum;
toxicity;
Drug Incompatibility;
Female;
Lethal Dose 50;
Male;
Mice;
Veratrum;
toxicity
- From:
China Journal of Chinese Materia Medica
2012;37(14):2139-2142
- CountryChina
- Language:Chinese
-
Abstract:
The compatible use of Veratrum nigrum with asarum, is one of the eighteen incompatible pairs. To research the toxic regularity of the compatible use of V. nigrum and asarum, this experiment adopted the uniform design combining with acute toxicity test, with the number of died animals as the observation indicator. The results showed that the toxicity came from the common effect of V. nigrum and asarum, and V. nigrum after the compatible use, and V. nigrum made a greater contribution to the toxicity caused by the compatible use. But the toxicity did not absolutely enhance with the increase in use of V. nigrum.
