Diffuse Bone Marrow Uptake of 99mTc-MIBI in A Case of Intravascular Large B-cell Lymphoma.
- Author:
Seung Hwan MOON
1
;
So Won OH
;
Jin Chul PAENG
;
Jin Ho PAIK
;
Dong Soo LEE
Author Information
1. Department of Nuclear Medicine, Seoul National University College of Medicine, Seoul, Korea. paengjc@snu.ac.kr
- Publication Type:Case Report
- Keywords:
Intravascular large B-cell lymphoma;
99mTc-MIBI;
18F-FDG PET
- MeSH:
B-Lymphocytes;
Bone Marrow;
Fluorodeoxyglucose F18;
Incidental Findings;
Lymphocytes;
Lymphoma;
Lymphoma, B-Cell;
Lymphoma, Large B-Cell, Diffuse
- From:Nuclear Medicine and Molecular Imaging
2009;43(4):352-356
- CountryRepublic of Korea
- Language:English
-
Abstract:
Intravascular large B-cell lymphoma (IVLBCL) is a subtype of diffuse large cell lymphoma, characterized by proliferation of lymphoid cells in the intravascular space of various organs without causing a mass effect. Although 18F-FDG PET is a powerful imaging tool in lymphoma, the usefulness of 18F-FDG PET in the assessment of IVLBCL is still controversial. 99mTc-MIBI, a tumor imaging radiopharmaceutical with a different mechanism from that of 18F-FDG, has been reported to be also effective in lymphoma. However, there is nearly no report on the efficacy of 99mTc-MIBI in the assessment of IVLBCL. We present one case of IVLBCL that showed 99mTc-MIBI accumulation in the involved bone marrow as an incidental finding, which was discrepant from that of 18F-FDG PET.
