A Neurofibroma Confused with Sarcomatous Transformation on F-18 FDG PET/CT in Neurofibromatosis-1.
- Author:
Soon Ah PARK
1
;
Jeong Hoon SONG
;
Chung Yong YANG
;
Hun Soo KIM
;
Seung Chol PARK
Author Information
1. Department of Nuclear Medicine, Wonkwang University College of Medicine, Iksan, Korea. nmbach@wonkwang.ac.kr
- Publication Type:Case Report
- Keywords:
PET/CT;
F-18 fluorodeoxyglucose;
neurofibromatosis
- MeSH:
Adult;
Electrons;
Humans;
Male;
Neurofibroma;
Neurofibromatoses
- From:Nuclear Medicine and Molecular Imaging
2009;43(4):361-362
- CountryRepublic of Korea
- Language:English
-
Abstract:
We present a patient with high 18F-fluorodeoxyglucose (FDG) uptake detected in a neurofibroma that was confused with sarcomatous transformation on a positron emission tomography/computed tomography (PET/CT) scan. A 39-year-old male patient with a 20-year history of neurofibromatosis-1 (NF-1) performed FDG PET/CT scan for the evaluation of lesions with sarcomatous transformation. The FDG PET/CT images demonstrated varying degrees of increased FDG uptake in the multiple nodules throughout whole body. The left pelvic mass with the highest FDG uptake had a maximum standardized uptake values (maxSUV) 5.0 and surgical resection was performed. Histological analysis confirmed the presence of a benign neurofibroma infiltrated with inflammatory cells.