Docetaxel-induced nail toxicity: a case of severe onycholysis and topic review.
- Author:
Chi-Pan LAU
1
;
Pun HUI
;
Tak-Cheung CHAN
Author Information
1. Department of Clinical Oncology, Prince of Wales Hospital, Shatin, Ngan Shing Street, New Territories, Hong Kong, China. patricklau75@hotmail.com
- Publication Type:Case Reports
- MeSH:
Adult;
Female;
Humans;
Nails;
drug effects;
pathology;
Onycholysis;
chemically induced;
Taxoids;
adverse effects
- From:
Chinese Medical Journal
2011;124(16):2559-2560
- CountryChina
- Language:English
-
Abstract:
Docetaxel is a commonly-used anti-cancer chemotherapeutic agent given its efficacy in a large variety of solid tumors. It is associated with various adverse effects one of which is nail toxicity. We report a case of severe onycholysis as a result of treatment with docetaxel in a patient who suffered from metastatic nasopharyngeal carcinoma. The case report will be followed by a discussion on the possible mechanism and preventive strategies for taxane-induced nail toxicity.
