Clinical Significance of Multiple Serum Tumor Markers in the Detection of Ovarian Carcinoma.
- Author:
Ho Sun CHOI
1
;
Yoon Sang OH
;
Moon Kyong CHO
;
Myoung Seon KANG
;
Woo Dae KANG
;
Sang Hyun PARK
;
Kwang Su LEE
;
Jin A HA
;
Myoung Sook JO
;
Seok Mo KIM
Author Information
1. Department of Obstetrics and Gynecology, Chonnam National University Medical School, Gwangju, Korea.
- Publication Type:Original Article
- Keywords:
Serum tumor markers;
CA125;
CA72-4;
CA19-9;
Ovarian tumors
- MeSH:
Humans;
Immunoradiometric Assay;
Reference Values;
Sensitivity and Specificity;
Biomarkers, Tumor*
- From:Korean Journal of Obstetrics and Gynecology
2003;46(9):1702-1706
- CountryRepublic of Korea
- Language:Korean
-
Abstract:
OBJECTIVE: This study evaluated the possible role of 2 additional tumor markers to CA125 in discriminating between benign and malignant ovarian tumors. METHODS: Serum samples from 1,346 patients were obtained on seven days before operation. All patients underwent surgery for ovarian tumors. Serum levels of 3 tumor markers were compared to histology. Concentrations of tumor markers (CA125, CA72-4, CA19-9) were detected by enzyme immuno- or immunoradiometric assays. Normal range of these markers was defined as CA125
