Relationship between insulin like hormone 3 and testicular descent and development.
- Author:
Xiao-jun XIE
1
;
Xue-Wu JIANG
Author Information
1. Department of Pediatric Surgery, the Second Hospital of Shantou University Medical College, Shantou, Guangdong 515041, China. xiexiaojun11908@tom.com
- Publication Type:Journal Article
- MeSH:
Animals;
Humans;
Insulin;
physiology;
Male;
Mice;
Mice, Knockout;
Proteins;
physiology;
Receptors, G-Protein-Coupled;
physiology;
Testis;
growth & development
- From:
National Journal of Andrology
2006;12(1):68-70
- CountryChina
- Language:Chinese
-
Abstract:
Testicular descent is an essential step in the course of reproductive system development. The mechanisms involved in the regulation of testis descent is not distinct. Gubernaculum has a very close relationship with testis descent. Maldescent of testis can cause abnormalities of genital system such as testicular underwent (cryptorchidism), dysplasia, tumor, infertility and low sexuality. Recently insulin like hormone 3 is a hotspot of concerning affecting gubernacular development and testicular descent. This article briefly reviews the advances in these aspects.
