Effects of experimental varicocele on methylenedioxyamphetamine, total antioxidants content and sialic acid of the epididymis in adolescent rats.
- Author:
Yu-Gang ZHAO
1
;
Hong-Bo SHI
;
Xue-Jun ZHANG
;
Ji ZHOU
;
Xiao-Wei MEN
;
Xin-Min ZHENG
;
Li-Quan HU
Author Information
- Publication Type:Journal Article
- MeSH: Animals; Antioxidants; metabolism; Epididymis; metabolism; Male; N-Acetylneuraminic Acid; metabolism; N-Methyl-3,4-methylenedioxyamphetamine; metabolism; Rats; Rats, Sprague-Dawley; Varicocele; metabolism
- From: National Journal of Andrology 2006;12(2):154-158
- CountryChina
- Language:Chinese
-
Abstract:
OBJECTIVETo explore the changes of methylenedioxyamphetamine (MDA), total antioxidants content (TAC) and sialic acid (SA) from the unilateral epididymis of experimental varicocele in adolescent rats, and to illuminate the effects of varicocele on unilateral epididymis epithelium.
METHODSExperimental left varicocele model of 16 adult male Sprague-Dawley rats were established by partial ligation of left renal vein. The epididymis were collected for detecting the content of MDA, TAC and SA by using spectrophotometry.
RESULTSThere was statistically significant differences in the contents of three substances between experimental varicocele and sham-operated groups.
CONCLUSIONThe content of MDA, TAC and SA will change and the sialic acid-secreting-function of unilateral epididymis will be injured because of varicocele.
