Clinical significance of prostatic-specific antigen levels in patients with benign prostatic hyperplasia complicated by low urinary tract syndrome.

Author: Ying-Jian ZHU ¹ ; Min YE ; Wei-Ming WANG ; Hai-Bo SHEN ; Jian-Hua CHEN ; Fang CHEN
Author Information

1. Department of Urology, Xinhua Hospital, Shanghai Jiao Tong University Medical College, Shanghai 200092, China.
Publication Type:Journal Article
MeSH: Aged; Aged, 80 and over; Enzyme-Linked Immunosorbent Assay; Humans; Male; Middle Aged; Prostate-Specific Antigen; blood; Prostatic Hyperplasia; blood; complications; Sensitivity and Specificity; Urethral Diseases; etiology
From: National Journal of Andrology 2006;12(2):156-158
CountryChina
Language:Chinese
Abstract:
OBJECTIVETo evaluate the clinical significance of prostatic-specific antigen (PSA) levels in patients with benign prostatic hyperplasia (BPH) complicated by low urinary tract syndrome( LUTS).
METHODSThe levels of tPSA, fPSA and fPSA/tPSA ratio were detected and compared in 520 cases of BPH with LUTS and 196 cases without LUTS.
RESULTSThe mean levels of tPSA in the cases of BPH with LUTS and without LUTS were (5.13 +/- 2.49) microg/L and (1.73 +/- 1.26) microg/L respectively (P<0.01). The mean levels fPSA were (1.57 +/- 0.80) microg/L and (0.54 +/- 0.38) microg/L respectively (P < 0.01). The mean ratios of fPSA/tPSA were (0.31 +/- 0.09) and (0.30 +/- 0.11) respectively ( P > 0.05).
CONCLUSIONThe levels of tPSA, fPSA are significantly higher in the cases of BPH with LUTS than those in the cases without LUTS, but the ratio of fPSA/tPSA is stable in BPH.