The effect of ethanol on sexual function of males and its mechanism.
- Author:
Xiu-Guo GAN
1
;
Rui-Hua AN
;
De-Bin ZHONG
Author Information
1. Department of Urology, the First Affiliated Hospital of Haerbin Medical University, Haerbin, Heilongriang 150001, China. ganxiuguo@yahoo.com.cn
- Publication Type:Journal Article
- MeSH:
Acetylcholinesterase;
metabolism;
Animals;
Ethanol;
pharmacology;
Hypothalamo-Hypophyseal System;
drug effects;
Male;
Nitric Oxide Synthase;
metabolism;
Penis;
cytology;
metabolism;
Rats;
Sexual Behavior, Animal;
drug effects;
Testosterone;
blood
- From:
National Journal of Andrology
2006;12(2):175-177
- CountryChina
- Language:Chinese
-
Abstract:
Though an adequate volume of ethanol relieves nervousness and enhances sexual desire,long term and excessive intake of ethanol can induce sexual dysfunction. The reasons that ethanol results in sexual dysfunction are as follows: ethanol inhibits the hypothalamo-pituitary-testes axis and decreases serum testosterone level. The decline of smooth muscle, choline acetyltransferase and nitric oxide synthase in the penis may be responsible for it.