Research on improving memory impairment of blue lavender volatile oil.
10.19540/j.cnki.cjcmm.20170928.011
- Author:
Li-Yun ZHU
1
;
Yong-Sheng GAO
1
;
Lin-Zhen SONG
1
;
Su-Fang LI
1
;
Jun-Qing QIAN
2
Author Information
1. Aromatic Engineering Technology Research and Develyment Center, China Jiliang University, Hangzhou 310018, China.
2. College of Biotechnology and Bioengineering, Zhejiang University of Technology, Hangzhou 310014, China.
- Publication Type:Journal Article
- Keywords:
antioxidant enzymes activity;
chemical composition;
lavender volatile oil;
memory impairment
- From:
China Journal of Chinese Materia Medica
2017;42(24):4819-4826
- CountryChina
- Language:Chinese
-
Abstract:
In order to study the potential application value of lavender volatile oil (LVO), the chemical composition of the volatile oil of lavender was analyzed by GC-MS, and the mouse model of Alzheimer's disease (AD) was established. Additionally, the antioxidant enzymes activity of T-SOD, GSH-PX, CAT and MDA content were studied. Experimental results showed that 55 kinds of chemical constituents including terpene, terpene alcohol and ester compounds from LVO were identified, and the content of linalool and linalyl acetate was the highest, accounting for 49.71% of the total volatile oil. The ability of mouse platform memory was improved significantly. The levels of GSH-PX, CAT and T-SOD of mouse brain tissue in the treatment group were significantly higher than those in the model group (P<0.05). The level of MDA reached the maximum value in the model group, while there was no notable difference between the levels of MDA in the drug group and the normal group. The result indicated the significant oxidative activity of LVO, the possibility of induced oxidative stress reduction in neurons, and the reversal effect of memory acquired disorder.
