Study of prognostic factors of ureter cancer.
- Author:
You-yan GUAN
1
;
Ning-chen LI
;
Li-qun ZHOU
;
Zhi-song HE
;
Ming LI
;
Yan-qun NA
Author Information
- Publication Type:Journal Article
- MeSH: Adult; Aged; Aged, 80 and over; Carcinoma, Transitional Cell; pathology; surgery; Female; Follow-Up Studies; Humans; Male; Middle Aged; Prognosis; Retrospective Studies; Survival Analysis; Ureteral Neoplasms; pathology; surgery
- From: Chinese Journal of Surgery 2007;45(18):1260-1263
- CountryChina
- Language:Chinese
-
Abstract:
OBJECTIVETo evaluate the prognostic factors of ureter transitional cell carcinoma (TCC).
METHODSBetween January 2001 and December 2005 133 TCC patients were treated. And the data was retrospectively analyzed.
RESULTSA mean age of the 133 patients was 68 years (range 43 - 87 years) at diagnosis. Altogether the non-invasive ureter TCC was found in 42 patients (31.6%) and the invasive ureter TCC in 91 patients (68.4%). Invasive ureter TCC growth was more common in distally located tumors (82.5%) compared to mid (62.5%) and proximal ureter (47.1%). Tumor stage, grade and location of the tumor were all correlated with disease specific survival in a univariate analysis. In a multivariate Cox analysis, tumor stage and grade were significantly associated with disease specific survival.
CONCLUSIONSMore invasive tumors are found in ureter than in bladder. Ureter cancer is more frequently found in the distal part. Distally located ureteral tumors are more likely invading into the muscular cell layers compared to proximally located tumors. Tumor stage and grade are still the more important prognostic factors for ureter TCC.
