Results of myasthenia gravis treated with thymectomy.
- Author:
Hai-tao ZHANG
1
;
De-ruo LIU
;
Yong-qing GUO
;
Bing-sheng GE
;
Yan-chu TIAN
;
Bin SHI
;
Chao-yang LIANG
Author Information
- Publication Type:Journal Article
- MeSH: Adolescent; Adult; Female; Follow-Up Studies; Humans; Male; Middle Aged; Muscle Weakness; etiology; prevention & control; Myasthenia Gravis; surgery; Postoperative Complications; prevention & control; Retrospective Studies; Thymectomy; adverse effects; methods; Treatment Outcome
- From: Chinese Journal of Surgery 2007;45(22):1546-1548
- CountryChina
- Language:Chinese
-
Abstract:
OBJECTIVETo evaluate the effectiveness of thymectomy for myasthenia gravis (MG) and the relative risk factors for postoperative myasthenic crisis.
METHODSThe clinic data of 78 cases with MG who underwent thymectomy from June 1985 to June 2005 were analyzed retrospectively. The relative risk factors of postoperative myasthenic crisis were analyzed and the differences between new and old region of perioperative management were compared.
RESULTSThe symptom of MG was complete remission in 21 cases, significantly improved in 38 cases, improved in 11 cases and unchanged in 8 cases, respectively. The symptom duration before operation, preoperative serum level of anti-acetylcholine receptor antibody, Osserman stage and pathological type of thymoma were independent relative risk factors for postoperative myasthenic crisis. The new region of perioperative management was significant better than the old one.
CONCLUSIONSurgical treatment shows significant clinical benefits for patients with MG.
