Construction of evaluation systems for traditional Chinese medicine multiple drug delivery system on basis of component level.
- Author:
Dan-hong YU
1
;
Dan LIU
;
Xiao-bin JIA
;
E SUN
;
Zhen-hai ZHANG
;
Wei XIAO
Author Information
1. Jiangsu Provincial Academy of Chinese Medicine, Nanjing 210028, China.
- Publication Type:Journal Article
- MeSH:
Biological Availability;
Drug Delivery Systems;
standards;
Drug Therapy;
standards;
Drugs, Chinese Herbal;
pharmacokinetics;
therapeutic use;
Evaluation Studies as Topic;
Humans;
Medicine, Chinese Traditional;
standards
- From:
China Journal of Chinese Materia Medica
2012;37(17):2667-2671
- CountryChina
- Language:Chinese
-
Abstract:
Traditional Chinese medicine (TCM) is a multi-component complex system and its research must consider its components characteristics of multi-component, multi-target and multi-effect. According to the whole concept of Chinese medicine, also combining with the status quo of Chinese drugs pharmaceutics and setting the material basis component as the premise, this study will develope TCM multiple drug delivery evaluation system, respectively from three aspects, namely in vitro release, in vivo bioavailability and PK-PD. At the same time, we will try to offer the new thoughts of the programly release, so as to provide new strategies and methods for the development of modern Chinese drug delivery systems.
