Randomized controlled clinical trial of kang'ai injection in gastrointestinal cancerchemotherapy patients.
- Author:
Yin CHEN
1
;
Mei-zuo ZHONG
;
Ming LU
Author Information
- Publication Type:Clinical Trial
- MeSH: Aged; Antineoplastic Combined Chemotherapy Protocols; adverse effects; therapeutic use; Case-Control Studies; Drugs, Chinese Herbal; administration & dosage; adverse effects; therapeutic use; Female; Fluorouracil; adverse effects; therapeutic use; Gastrointestinal Neoplasms; drug therapy; pathology; Humans; Leucovorin; adverse effects; therapeutic use; Male; Middle Aged; Neoplasm Staging; Organoplatinum Compounds; adverse effects; therapeutic use; Treatment Outcome
- From: China Journal of Chinese Materia Medica 2012;37(19):2990-2992
- CountryChina
- Language:Chinese
-
Abstract:
OBJECTIVETo study the influence of kang'ai injection on quality of life among gastrointestinal cancer chemotherapy patients.
METHODFourty-two gastrointestinal cancer patients were randomly divided into the treatment group (n=22) and the control group (n=20). The treatment group was treated with chemotherapy and kang'ai injection, and the control group was only treated with chemotherapy. Their quality of life, improvement of clinical symptoms and adverse effects were observed.
RESULTThe disease control rates of the treatment group and the control group were 91% and 30% ,while their effective rates of KPS were 59% and 30% respectively. They had one case and six cases with side effects above III degree.
CONCLUSIONKang'ai injection can mitigate syndromes of gastrointestinal cancer chemotherapy patient, improve their quality of life and have an effect of reducing toxic and enhancing efficacy for chemotherapy.
