Investigation of clinical practice and side effects of Shenfu injection.
- Author:
Ying-Kun FU
1
;
Yan-Ming XIE
Author Information
- Publication Type:Journal Article
- MeSH: Clinical Trials as Topic; Drug-Related Side Effects and Adverse Reactions; Drugs, Chinese Herbal; administration & dosage; adverse effects; Female; Humans; Male
- From: China Journal of Chinese Materia Medica 2012;37(18):2796-2799
- CountryChina
- Language:Chinese
-
Abstract:
OBJECTIVETo investigate the status of clinical practices and side effects related to Shenfu injection.
METHODIt was searched the Chinese medical citation index (CMCI) database and China national knowledge infrastructure (CNKI) database using the word "Shenfu injection". Original clinical studies of Shenfu injection which were published from January 1 987 to March 2012 in Chinese magazines were included.
RESULTA total of 1 433 relevant clinical studies were identified. It was investigated and analyzed the side effects of Shenfu injection. For cases with side effects, the diseases for treatment, the medication dosage, the course, and menstrum of treatment for the side effects were evaluated. All the side effects were mild except five cases of serious adverse reaction.
CONCLUSIONShenfu injection has been widely used in clinical patients since it came into the market in 1987. However, there are some problems in its clinical practices, such as deficiency in selecting and expanding diseases for treatment, evaluating the dosage and treatment method. Therefore, it is imperative to evaluate drugs by literature and good clinical application after the drugs come into the market with evidence-based medicine.
