Relevance between quality craft and safe medication of Shuxuetong injection.
- Author:
Meng WANG
1
;
Jian ZHANG
Author Information
1. Renmin University of China, Beijing 100872, China. iceangella@126.com
- Publication Type:Journal Article
- MeSH:
Animals;
Drug Therapy;
standards;
Drugs, Chinese Herbal;
administration & dosage;
adverse effects;
chemistry;
standards;
Humans;
Leeches;
chemistry;
Medicine, Chinese Traditional;
standards;
Molecular Weight;
Oligochaeta;
chemistry;
Quality Control
- From:
China Journal of Chinese Materia Medica
2012;37(18):2818-2819
- CountryChina
- Language:Chinese
-
Abstract:
Shuxuetong (SXT) injection is the first animal original injection in traditional Chinese medicine, the main component are the leech and the earthworm. SXT has got five national invention patents, and is recognized as the most potent medicine expelling blood stasis agent, which indication is the only one be clearly approved by SFDA as the acute phase of cerebral infarction. Modern biological extraction technology is adopted to prepare SXT, the entire production process using only saline as a solvent. Patented product process is induced to maximize the retention of medicinal components and activity, as well as to remove invalid substances as variant protein,high molecular weight substances which causes allergic reactions. SXT have been isolated and identified class 7 of56 compounds, the molecular weight is from 100 to 1 700 Da, mainly including peptides, glycopeptides, endogenous small molecules.
