Analysis and thinking on status of constituent library of traditional Chinese Medicines in China.
- Author:
Li-Mei ZHAO
1
;
Ning-Hua TAN
Author Information
1. State Key Laboratory of Phytochemistry and Plant Resources in West China, Kunming Institute of Botany, Chinese Academy of Sciences, Kunming 650201, China.
- Publication Type:Journal Article
- MeSH:
China;
Databases, Chemical;
Drugs, Chinese Herbal;
chemistry;
Medicine, Chinese Traditional;
instrumentation
- From:
China Journal of Chinese Materia Medica
2012;37(20):3012-3016
- CountryChina
- Language:Chinese
-
Abstract:
Natural products from traditional Chinese medicines (TCMs) are one of the important sources for drug discovery. Systematic investigation on chemical constituents of TCMs plays one key role in TCMs R & D. Research and development on the constituent library of TCMs including the constituent repository and database (eCL-TCMs) is significant for the modernization of TCMs and new drug R & D. This paper reviews the status of current compound libraries and databases in China, analyzes some key problems, and proposes the necessity and ideas of the running eCL-TCMs supported by the National New Drug Innovation Great Project of China (2011ZX09307-002-02). The eCL-TCMs are large-scale, high-quality, comprehensive, standard, open-access, and are integrated with quality control system, drug screening and discovery platforms.
