Application of microwave technology in extraction process of Guizhi Fuling capsule.
- Author:
Zheng-kuan WANG
;
Mao ZHOU
;
Yuan LIU
;
Yu-an BI
;
Zhen-zhong WANG
;
Wei XIAO
- Publication Type:Journal Article
- MeSH:
Capsules;
Chromatography, High Pressure Liquid;
Drugs, Chinese Herbal;
isolation & purification;
Microwaves;
Technology, Pharmaceutical;
methods
- From:
China Journal of Chinese Materia Medica
2015;40(11):2123-2127
- CountryChina
- Language:Chinese
-
Abstract:
In this paper, optimization of the conditions of microwave technique in extraction process of Guizhi Fuling capsule in the condition of a pilot scale was carried out. First of all, through the single factor experiment investigation of various factors, the overall impact tendency and range of each factor were determined. Secondly, L9 (3(4)) orthogonal test optimization was used, and the contents of gallic acid in liquid, paeoniflorin, benzoic acid, cinnamic acid, benzoyl paeoniflorin, amygdalin of the liquid medicine were detected. The extraction rate and comprehensive evaluation were calculated with the extraction effect, as the judgment basis. Theoptimum extraction process of Guizhi Fuling capsule by microwave technology was as follows: the ratio of liquid to solid was 6: 1 added to drinking water, the microwave power was 6 kW, extraction time was 20 min for 3 times. The process of the three batch of amplification through verification, the results are stable, and compared with conventional water extraction has the advantages of energy saving, time saving, high efficiency advantages. The above results show the optimum extracting technology of high efficiency, stable and feasible.
