A new bisabolane-type sesquiterpenoid from Coreopsis tinctoria.
- Author:
Jin-jun LIU
;
Yin-jun YANG
;
Yin-di ZHU
;
Guang-zhi LI
;
Wen-hua HUANG
;
Bao-lin GUO
- Publication Type:Journal Article
- MeSH:
Coreopsis;
chemistry;
Sesquiterpenes;
chemistry;
isolation & purification
- From:
China Journal of Chinese Materia Medica
2015;40(11):2132-2137
- CountryChina
- Language:Chinese
-
Abstract:
To study the chemical constituents of the inflorescences of Coreopsis tinctoria from Xinjiang, isolation and purification of constituents were carried out by column chromatography on macroporous resin (D101) , MCI gel, MDS gel, silica gel, Sephadex LH-20 and semi-preparative HPLC. The structures of the compounds were identified by physicchemical properties and spectral data analysis. Fourteen compounds were isolated and identified as coretinterpenoid A (1), coretinphenol (2), quercetin (3), quercetin-3-O-β-glucopyranoside (4), luteolin (5), taxifolin (6), 7, 3', 5'-trihydroxyflavanone (7), isookanin (8), isookanin-7-O-β-D-glucopyranoside (9), 5, 7, 3', 5'-tetrahydroxyflavanone-7-O-β-D-glucopyranoside (10), butein (11), okanin (12), sulfuretin (13), and linocinnamarin (14). Compound 1 was a new isabolane-type sesquiterpenoid and compounds 4, 10 and 13 were isolated from this plant for the first time.