Effect of Guizhi Fuling capsule and combination of active ingredients on rats with uterine myoma.
- Author:
Qing-qing HENG
;
Liang CAO
;
Na LI
;
Gang DING
;
Zhen-zhong WANG
;
Wei XIAO
- Publication Type:Journal Article
- MeSH:
Animals;
Capsules;
Drugs, Chinese Herbal;
therapeutic use;
Estradiol;
blood;
Female;
Leiomyoma;
blood;
drug therapy;
pathology;
Progesterone;
blood;
Rats;
Rats, Wistar;
Uterine Neoplasms;
blood;
drug therapy;
pathology
- From:
China Journal of Chinese Materia Medica
2015;40(11):2206-2209
- CountryChina
- Language:Chinese
-
Abstract:
It is to observe the therapeutic action of Guizhi Fuling capsule and the combination of active ingredients on model rats with uterine leiomyoma. The hysteromyoma rats models was established in rats by loading eatrogen, to observe the effect on pathological condition of uterus, uterus wet weight, the content of estradiol and progesterone. Guizhi Fuling capsule and the combination of active ingredients remarkably decreased uterus weight, restrained the excess proliferation of the smooth muscle of uterus, decreased the estraiol and progesterone in blood serum. Guizhi Fuling capsule and the combination of active ingredients can restrain the formation of hysteromyoma in a dose-dependent manner. Perhaps the combination of active ingredients is the material foundation of antihysteromyoma.
