Determination of residual aluminium Ion in Huoxiang Zhengqi pellets by GFAAS with EDTA complexation extraction.
- Author:
Xue-Na WANG
;
Cong-Cong RAN
;
Qing-Lian LI
;
Chao-Hui DU
;
Ye JIANG
- Publication Type:Journal Article
- MeSH:
Aluminum;
chemistry;
isolation & purification;
Drug Contamination;
Drugs, Chinese Herbal;
chemistry;
Edetic Acid;
chemistry;
Graphite;
chemistry;
Spectrophotometry, Atomic;
methods;
Temperature
- From:
China Journal of Chinese Materia Medica
2015;40(12):2345-2348
- CountryChina
- Language:Chinese
-
Abstract:
To establish an EDTA complexation extraction pretreatment combining with GFAAS method for the determination of residual aluminium ion in Huoxiang zhengqi pellets without digestive treatment, systematical investigation was made on sample preparation, and EDTA was used for the complexation extraction of residual aluminium ion in samples. The pH, concentration and volume of extraction solution, the temperature and time of microwave extraction, and graphite furnace temperature program were investigated. The results were compared with the microwave digestion. It was showed that, 0.1 g of sample weight was added in 20 mL 0.05 mol x L(-1) EDTA solution (pH 3.5), followed by heating at 150 degrees C for 10 min in the microwave extraction device. The determination of GFAAS was performed at optimized detection wavelength (257.4 nm) as well as graphite furnace temperature program, the detection limits and quantification limits were 2.37 μg x L(-1) and 7.89 μg x L(-1), respectively. The precision (RSD) was less than 2.3%. The average recovery was 96.9% -101%. The present method is easy, rapid and accurate for the determination of residual aluminium ion in Huoxiang zhengqi pellets.
