Cystic lymphoid hyperplasia of the parotid gland as the initial manifestation of HIV infection.
- Author:
Bingcheng WU
1
;
Raymond NGO
;
Fredrik PETERSSON
Author Information
1. Department of Pathology, National University Health System, 5 Lower Kent Ridge Road, Singapore 119074. fredrikpetersson@live.se.
- Publication Type:Case Reports
- MeSH:
Adult;
B-Lymphocytes;
cytology;
Biopsy;
Epithelial Cells;
cytology;
Epithelium;
metabolism;
HIV Infections;
diagnosis;
Humans;
Hyperplasia;
pathology;
virology;
Immunohistochemistry;
Lymphocytes;
cytology;
Male;
Parotid Gland;
pathology;
virology;
Salivary Glands;
pathology;
Tomography, X-Ray Computed
- From:Singapore medical journal
2014;55(1):e12-6
- CountrySingapore
- Language:English
-
Abstract:
We report the case of a patient who presented with cystic lymphoid hyperplasia of the right parotid gland as the index diagnosis of HIV infection. Histological examination of the excised parotid gland revealed a solid-cystic lymphoepithelial lesion with a non-keratinous squamous epithelium, which grew into the lymphoid component via anastomosing cords and islands. These anastomosing cords and islands contained variably abundant B cells, several subepithelial multinucleated histiocytes, salivary ducts infiltrated by small lymphocytes, and a dense lymphoid infiltrate containing lymphoid follicles with enlarged, irregular germinal centres.
