Isoniazid-induced cerebellitis: a disguised presentation.
- Author:
Prasant PETER
1
;
Mary JOHN
Author Information
1. Department of Radiodiagnosis, Christian Medical College and Hospital, Ludhiana, Punjab, Pin-141008, India. prasant.peter@rediffmail.com.
- Publication Type:Case Reports
- MeSH:
Adult;
Antitubercular Agents;
adverse effects;
Cerebellar Diseases;
chemically induced;
Cerebellar Nuclei;
pathology;
Diagnosis, Differential;
Female;
Humans;
Isoniazid;
adverse effects;
Magnetic Resonance Imaging;
Renal Dialysis;
Renal Insufficiency;
therapy;
Tuberculosis;
drug therapy
- From:Singapore medical journal
2014;55(1):e17-9
- CountrySingapore
- Language:English
-
Abstract:
Cerebellitis is a rarely encountered complication of isoniazid therapy. Its occurrence is usually associated with concomitant renal disease and haemodialysis. Herein, we report the case of a patient with this complication who presented with isolated bilateral symmetrical dentate nucleus T2 hyperintensities on magnetic resonance imaging. Isoniazid neurotoxicity has never been reported to cause bilateral dentate hyperintensities, for which the differentials are few and include metronidazole toxicity.
