Dystrophic Epidermolysis Bullosa in Two Sisters.
- Author:
Byung Jun AHN
;
Hyo Chan JANG
;
Sang Won KIM
;
Chi Dong HAN
- Publication Type:Original Article
- Keywords:
Dystrophic epidermolysis bullosa;
Two sisters
- MeSH:
Abdomen;
Basement Membrane;
Buttocks;
Epidermolysis Bullosa Dystrophica*;
Extremities;
Humans;
Parturition;
Siblings*;
Thorax;
Ulcer
- From:Korean Journal of Perinatology
1999;10(4):485-489
- CountryRepublic of Korea
- Language:Korean
-
Abstract:
Dystrophic epidermolysis bullosa is a rare, chronic non-inflammatory bullous disease, which easily forms bullae by minor mechanical trauma or spontaneously, is inherited either in an autosomal dominant or autosomal recessive fashion. We report herein two cases which presented with bullae, erosions and ulcers on extremities, buttock, chest, abdomen and face and loss of all nail since birth in two sisters. Bulla occured bencath the basal lamina histopathologically, anchoring fibrils were almost absent on electron miaoscopy in both cases. The two sisters represented dystrophic epidermolysis bullosa considering the absence of family history inheritcd in an autosomal dominant fashion and the clinical, histological and electronmicroscopic findings.
