Change of platelet count and P-selectin in preserved platelet concentrates.
- Author:
Hui-Fang NIE
1
;
Bao-Qing LUI
;
Run-Ling ZHANG
;
Yu-Chun ZHANG
;
Zhi-Feng ZHANG
;
Chun-Fang YUAN
Author Information
1. The Red Cross Blood Center of Gansu Province, Lanzhou 730046, China. gsxyzx@public.LZ.GS.cn
- Publication Type:Journal Article
- MeSH:
Blood Platelets;
chemistry;
Blood Preservation;
Female;
Humans;
Male;
P-Selectin;
blood;
Platelet Count;
Time Factors
- From:
Journal of Experimental Hematology
2002;10(6):571-573
- CountryChina
- Language:Chinese
-
Abstract:
To observe the change of quantity and quality of platelets preserved in a full-sealed bag, and explore the difference of platelets preserved in oscillating and static conditions at (22 +/- 2) degrees C, the platelet concentrates were prepared with a CS-3000-plus blood cell separator, the platelet counts were performed with automatic blood cell analyzer and P-selectin in supernatant of platelet concentrates was detected by ELISA. The results showed that both of platelet count and P-selectin content in the platelet concentrates had no significant difference between oscillating and static preservation condition. With prolongation of preserved time, the platelet count decreased and P-selectin content increased gradually in both preserved conditions. There was no difference in the platelet counts during 0 - 72 hours preservation in both conditions, and significant difference was seen in 96 - 120 hours preservation. It was concluded that the expired date for platelet product preserved in CS-3000-plus blood cell separator full-sealed system should be 3 days. Under the condition of (22 +/- 2) degrees C, the quality of the platelet preserved in oscillating state is not superior to static preservation.
