Statistical analysis of 4000 umbilical cord blood units preserved in shandong cord blood bank.
- Author:
Jie PAN
1
;
Shen-Li ZHOU
;
Bai-Jun SHEN
;
Wen-Ying YAN
;
Ri XU
;
Dao-Gang SONG
Author Information
1. Shandong Cord Blood Bank, Jinan 250002, China. Panjie@sinocord.com
- Publication Type:Journal Article
- MeSH:
Antigens, CD34;
immunology;
Blood Banks;
Blood Preservation;
Cell Count;
China;
Data Interpretation, Statistical;
Fetal Blood;
cytology;
immunology;
metabolism;
Gene Frequency;
HLA-A Antigens;
genetics;
HLA-B Antigens;
genetics;
HLA-DR Antigens;
genetics;
Humans;
Leukocyte Count;
Leukocytes;
cytology;
immunology;
Time Factors
- From:
Journal of Experimental Hematology
2002;10(3):257-260
- CountryChina
- Language:Chinese
-
Abstract:
The current study analyzed the data of 4 000 umbilical cord blood (UCB) units collected in Shandong Cord Blood Bank from the end of 1999 to March 2001. The averages of nucleated cells and CD34(+) cells were more than 1.2 x 10(9) and 3.9 x 10(6) per UCB unit respectively, and more than 1.5 x 10(9) nucleated cells per UCB unit were obtained in 768 UCB units. These UCB units are suitable for transplantation in patients with a body weight greater than 40 kg. The analysis of HLA gene frequency showed that A2, A24, A11, B13, B51, DR15, DR7 and DR9 are the common halotypes in Shandong population and similar to those in the other areas of China. 40% patients could search out at least 1 UCB unit with 1 mismatched HLA locus in Shandong Cord Blood Bank.
