Progress in microRNAs associated with major avian viruses.
- Author:
Chaolai MAN
;
Weitao MU
;
Dongxue ZHAO
;
Yang CHANG
- Publication Type:Journal Article
- MeSH:
Animals;
Avian Leukosis;
Birds;
virology;
Birnaviridae Infections;
Herpesviridae;
genetics;
Influenza in Birds;
MicroRNAs;
genetics
- From:
Chinese Journal of Biotechnology
2015;31(9):1289-1300
- CountryChina
- Language:Chinese
-
Abstract:
Recently, avian viral diseases have become one of the main models to study mechanisms of viral infections and pathogenesis. The study of regulatory relationships and mechanisms between viruses and microRNAs has also become the focus. In this review, we briefly summarize the general situations of microRNAs encoded by avian herpesviruses. Also, we analyze the regulatory relationships between tumorigenicity of avian herpesviruses and microRNAs. Additionally, the possible applications for prevention and treatment of viral diseases (such as infectious bursal disease, avian influenza and avian leucosis) using the regulatory mechanisms of microRNAs are also discussed.