Herb-induced cardiotoxicity from accidental aconitine overdose.
- Author:
Sujata SHETH
1
;
Elaine Ching Ching TAN
1
;
Hock Heng TAN
2
;
Leslie TAY
3
Author Information
- Publication Type:Case Reports
- Keywords: aconite; aconitine herb; bidirectional ventricular tachycardia; cardiotoxic; overdose
- MeSH: Aconitine; poisoning; Adult; Anti-Arrhythmia Agents; therapeutic use; Cardiopulmonary Resuscitation; Cardiotoxicity; Drug Overdose; Drugs, Chinese Herbal; poisoning; Electric Countershock; Electrocardiography; Humans; Male; Tachycardia; chemically induced; Tachycardia, Ventricular; chemically induced; Treatment Outcome; Ventricular Fibrillation; chemically induced
- From:Singapore medical journal 2015;56(7):e116-9
- CountrySingapore
- Language:English
- Abstract: Patients who overdose on aconite can present with life-threatening ventricular arrhythmia. Aconite must be prepared and used with caution to avoid cardiotoxic effects that can be fatal. We herein describe a case of a patient who had an accidental aconite overdose but survived with no lasting effects. The patient had prepared Chinese herbal medication to treat his pain, which resulted in an accidental overdose of aconite with cardiotoxic and neurotoxic effects. The patient had ventricular tachycardia, bidirectional ventricular tachycardia and ventricular fibrillation. Following treatment with anti-arrhythmic medications, defibrillation and cardiopulmonary resuscitation, he made an uneventful recovery, with no further cardiac arrhythmias reported.
